Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

pH regulation and swimbladder function in fish.

Bernd Pelster1

  • 1Institut für Zoologie und Limnologie, Universität Innsbruck, A-6020 Innsbruck, Austria. bernd.pelster@uibk.ac.at

Respiratory Physiology & Neurobiology
|November 24, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of CO<sub>2</sub> for Gas Secretion in a Physoclist Swimbladder.

Acta physiologica (Oxford, England)·2026
Same author

Nitrogen excretion and oxygen consumption under severe hypoxia in siluriform fishes from the Amazon.

Journal of fish biology·2025
Same author

Oxygen consumption from air and water, ammonia and urea-N excretion, and Na<sup>+</sup> fluxes during progressive aquatic hypoxia in Amazonian armoured catfish Pterygoplichthys gibbiceps and Pterygoplichthys pardalis.

Journal of fish biology·2025
Same author

Is the air-breathing organ a significant route for CO<sub>2</sub> excretion during aquatic hypercapnia in the pirarucu, Arapaima gigas?

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology·2024
Same author

The multifunctional fish gill.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology·2024
Same author

The physiological consequences of a very large natural meal in a voracious marine fish, the staghorn sculpin (Leptocottus armatus).

The Journal of experimental biology·2023
Same journal

Physiological responses during a maximal dry static breath-hold in a world champion freediver.

Respiratory physiology & neurobiology·2026
Same journal

Intermittent Hypoxemia in Preterm Infants: Glial Fibrillary Acidic Protein as a Potential Brain Injury Biomarker.

Respiratory physiology & neurobiology·2026
Same journal

Asymmetry of thoracic expansion in hemiplegic stroke and its relationship with physical function and percent vital capacity: A cross-sectional study.

Respiratory physiology & neurobiology·2026
Same journal

Evaluating the shape of the expiratory flow volume curve in asymptomatic ex-smokers.

Respiratory physiology & neurobiology·2026
Same journal

Emphysema and airway disease synergistically impair exercise tolerance in smokers: A CT-based study.

Respiratory physiology & neurobiology·2026
Same journal

Oxygen extremes, inflammation, and neonatal breathing.

Respiratory physiology & neurobiology·2026
See all related articles

European eel gas gland cells maintain acidic intracellular pH for proton secretion via multiple pathways. Mechanisms regulating these processes and cellular metabolism remain largely unknown.

Area of Science:

  • Physiology
  • Cell Biology
  • Biochemistry

Background:

  • Gas gland cells in European eels (Anguilla anguilla) are specialized for acid metabolite production and secretion.
  • These cells operate under high oxygen but primarily metabolize glucose to lactate and CO2, with minimal aerobic oxidation.

Purpose of the Study:

  • To investigate the mechanisms of proton secretion in European eel gas gland cells.
  • To understand how intracellular pH is maintained and regulated under varying extracellular conditions.

Main Methods:

  • Analysis of metabolic pathways (glucose conversion to lactate and CO2).
  • Assessment of proton extrusion mechanisms including CO2 diffusion, Na+/H+-exchange, anion exchange, and V-ATPase.
  • Evaluation of pH regulation and buffering capacity.

Related Experiment Videos

Main Results:

  • Gas gland cells maintain an acidic intracellular pH (0.2-0.3 units lower than extracellular).
  • Proton secretion occurs via CO2 diffusion, Na+/H+-exchange, anion exchange, and V-ATPase.
  • Dominant pathways shift with intracellular pH: sodium-dependent pathways and CO2 diffusion at rest, with increased Na+/H+-exchange and V-ATPase at lower intracellular pH.

Conclusions:

  • European eel gas gland cells actively regulate intracellular acidity to facilitate proton extrusion.
  • Multiple transport systems contribute to acid secretion, with adaptable roles based on physiological conditions.
  • Regulatory mechanisms for these pathways and underlying metabolism require further investigation.