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Updated: Aug 17, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Peptide self-assembly as a model of proteins in the pre-genomic world
Indraneel Ghosh1, Jean Chmielewski
1Department of Chemistry, University of Arizona, 1306 E. University Blvd, Tuscon, AZ 85721, USA. ghosh@email.arizona.edu
Abstract:
Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.
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