Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optical section retinal imaging and wavefront sensing in diabetes.

Mahnaz Shahidi1, Norman P Blair, Marek Mori

  • 1Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA. mahnshah@uic.edu

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|November 24, 2004
PubMed
Summary

Diabetic eyes show increased higher-order ocular aberrations, leading to reduced retinal image resolution. This finding is crucial for developing advanced retinal imaging technologies for diabetic patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Racial Variations in Retinal Oxygen Metabolic Biomarkers in Diabetic Retinopathy: A Pilot Study.

Journal of ophthalmology·2026
Same author

Association of papilledema severity with retinal vessel tortuosity in idiopathic intracranial hypertension.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Diagnosis of High Intracranial Pressure by Non-Optic Nerve Retinal Image Features.

Translational vision science & technology·2026
Same author

Retinal Hypoxia: Relation to Blood Flow and Oxygen Metabolic Biomarkers.

Investigative ophthalmology & visual science·2026
Same author

A Method for Peripapillary Retinal Vessel Tortuosity Measurement and Its Clinical Correspondence.

Translational vision science & technology·2025
Same author

Conjunctival Venular Hemodynamic Biomarkers in Glaucoma.

Translational vision science & technology·2025

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Diabetic Retinopathy Research

Background:

  • Diabetic retinopathy is a leading cause of vision loss.
  • Understanding ocular changes in diabetes is vital for early detection and management.
  • Ocular aberrations can impact retinal imaging quality.

Purpose of the Study:

  • To compare higher-order ocular aberrations between healthy and diabetic individuals.
  • To assess differences in optical section retinal image resolution in these groups.
  • To explore the relationship between aberrations and image resolution in diabetic eyes.

Main Methods:

  • Developed a combined retinal optical section imaging and wavefront sensing system.
  • Utilized a Shack-Hartmann aberrometer for aberration measurement.

Related Experiment Videos

  • Analyzed data from 22 diabetic and 13 healthy subjects using statistical tests.

    • Main Results:

    • Diabetic subjects exhibited significantly higher higher-order ocular aberrations (p=0.03).
    • Retinal image depth resolution was significantly lower in diabetic subjects (p <0.001).
    • A significant inverse correlation was found between resolution and aberrations (r=-0.5; p=0.007).

    Conclusions:

    • Diabetes is associated with increased higher-order ocular aberrations.
    • These aberrations negatively impact retinal image resolution in diabetic eyes.
    • Findings inform the design of high-resolution retinal imaging for retinal diseases.