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Repeatability and effects of sequential measurements with POBF tonograph
Pinakin Gunvant1, Russell Julian Watkins, David Charles Broadway
1Department of Psychological and Brain Sciences, University of Louisville, Louisville, Kentucky 40292, USA. contact@pinakin-gunvant.com
Summary
Repeated intraocular pressure (IOP) measurements with the Pulsatile Ocular Blood Flow (POBF) Tonograph show a decrease, especially with shorter intervals. For accurate IOP readings, allow at least 2-15 minutes between POBF Tonograph measurements.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Medical Instrumentation
Background:
- Intraocular pressure (IOP) is a critical factor in diagnosing and managing glaucoma.
- Accurate and repeatable IOP measurements are essential for effective patient care.
- The Pulsatile Ocular Blood Flow (POBF) Tonograph is a device used for measuring IOP and ocular blood flow.
Purpose of the Study:
- To evaluate the impact of sequential measurements using the POBF Tonograph on IOP and POBF readings.
- To determine if measuring the fellow eye affects IOP.
- To assess the repeatability of measurements obtained with the POBF Tonograph.
Main Methods:
- 46 healthy adults participated in the study.
- Subjects underwent sequential POBF Tonograph measurements with varying time intervals (1-15 minutes).
- Repeatability was assessed using intraclass correlation coefficient and Bland-Altman plots.
Main Results:
- Repeated IOP measurements showed a significant decrease, particularly with shorter intervals (1 minute).
- No significant changes were observed in POBF values across repeated measurements.
- Single measurements on the fellow eye did not significantly alter IOP.
Conclusions:
- For reliable IOP measurements with the POBF Tonograph, a minimum interval of 2 minutes, preferably 15 minutes, is recommended between sequential readings.
- The POBF Tonograph demonstrated no significant immediate effect on IOP or POBF values of the fellow eye.