Prostatic carcinoma: problems in the interpretation of prostatic biopsies

We have endeavored to identify problems the pathologist may face in dealing with prostatic carcinoma (PCa). We have covered criteria for diagnosis and have discussed lesions that simulate PCa and the distinguishing features, treatment effects, and specific types of PCa. In many of these areas there is a need for developing objective, reproducible, and measurable criteria. The need for research is obvious.