Related Experiment Video
Updated: Aug 20, 2026

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
Ischemic optic neuropathy in dialyzed patients: a previously unrecognized manifestation of calcific uremic
Asher Korzets1, Idit Marashek, Ariel Schwartz
1Department of Nephrology, Rabin Medical Center (Campus Golda), Petach Tikva, Israel. asherko@clalit.org.il
Abstract:
Two patients with end-stage renal disease and on long-term hemodialysis presented with hypotension and an acute unilateral loss of vision. A diagnosis of anterior ischemic optic neuropathy (AION) was made quickly, but despite high-dose steroid therapy, significant vision was not recovered. Temporal artery biopsy results showed extensive medial calcification. The possibility that hypotension, when coupled with calcific uremic arteriolopathy in arteries supplying the optic nerve head, will lead to AION in dialyzed patients is discussed. A short review of AION in the dialysis population is given.
Related Concept Videos
Diabetic Nephropathy
Diabetic Retinopathy
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Glaucoma: Overview
Peripheral Artery Disease I: Introduction
Diabetic Neuropathy
