Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Enhanced ultrafiltration using 7.5% icodextrin/1.36% glucose combination dialysate: a pilot study.

Fiona Dallas1, Sarah B Jenkins, Martin E Wilkie

  • 1Sheffield Kidney Institute, Sheffield, United Kingdom.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|November 24, 2004
PubMed
Summary

A new combination dialysate significantly improved fluid removal in peritoneal dialysis (PD) patients. This novel solution increased long-dwell and 24-hour ultrafiltration volumes, offering a potential advancement in PD therapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis patients.

The Cochrane database of systematic reviews·2023
Same author

Home dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Kidney international·2023
Same author

Serologic Responses following a Single Dose of SARS-Cov-2 Vaccination in Allogeneic Stem Cell Transplantation Recipients.

Transplantation and cellular therapy·2021
Same author

Advanced Laparoscopic Peritoneal Dialysis Catheter Insertion: Systematic Review and Meta-Analysis.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2018
Same author

Longitudinal bioimpedance vector plots add little value to fluid management of peritoneal dialysis patients.

Kidney international·2015
Same author

Respecting shape memory to optimize peritoneal dialysis catheter outcomes.

Kidney international·2014

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Peritoneal Dialysis

Background:

  • Peritoneal dialysis (PD) is a crucial renal replacement therapy.
  • Optimizing fluid management, particularly ultrafiltration, is key in PD.
  • Icodextrin-based solutions are used for long dwell times in PD.

Purpose of the Study:

  • To evaluate a novel combination dialysate (7.5% icodextrin/1.36% glucose) against 7.5% icodextrin alone for long dwell in PD.
  • To assess the impact on ultrafiltration and other key parameters.

Main Methods:

  • A 4-week prospective, randomized crossover pilot study.
  • Involved 8 patients on continuous ambulatory PD (CAPD) or automated PD.
  • Measured long-dwell and 24-hour ultrafiltration, body weight, blood pressure, and medication use.

Related Experiment Videos

Main Results:

  • Combination dialysate increased median long-dwell ultrafiltration by 33% (750 mL to 1000 mL, p < 0.001).
  • 24-hour ultrafiltration increased by 29% (739 mL to 956 mL, p < 0.001).
  • Body weight, blood pressure, and antihypertensive/diuretic tablet counts remained stable.

Conclusions:

  • The novel combination dialysate significantly enhances ultrafiltration in PD patients.
  • This suggests a promising new option for fluid management in peritoneal dialysis.
  • Further research may validate its role in improving PD outcomes.