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Thermodynamics of interaction of phthalocyanine-oligonucleotide conjugates with single- and double-stranded DNA
A A Chernonosov1, N A Kuznetsov, V V Koval
1Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia.
Abstract:
Thermodynamics of interaction of phthalocyanine-oligonucleotide conjugates with single- and double-stranded DNA resulting in formation of duplexes and triplexes was measured by UV melting method. It was shown that a phthalocyanine moiety of conjugates stabilized the formation of duplexes and triplexes.
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