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Assay Development for High-Throughput Drug Screening Against Mycobacteria
Published on: October 25, 2024
A subinhibitory concentration of clarithromycin inhibits Mycobacterium avium biofilm formation
George Carter1, Lowell S Young, Luiz E Bermudez
1Kuzell Institute, California Pacific Medical Center Research Institute, San Francisco, California, USA.
Antimicrobial Agents and Chemotherapy
|November 25, 2004
Abstract:
Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.
