Related Experiment Video

Updated: Aug 20, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

Published on: May 3, 2018

Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes

Michael J Haller1, Margaret Samyn, Wilmer W Nichols

  • 1Pediatric Endocrinology, P.O. Box 100296, Gainesville, FL 32610, USA. hallemj@peds.ufl.edu

Diabetes Care
|November 25, 2004
PubMed

Insights

Children with type 1 diabetes show increased arterial stiffness, a key indicator of cardiovascular risk. Radial artery tonometry is a simple, noninvasive method to assess this in pediatric patients.

Area of Science:

  • Pediatric Cardiology
  • Vascular Physiology
  • Diabetes Research

Background:

  • Type 1 diabetes (T1D) is a chronic condition affecting children.
  • Cardiovascular complications are a significant concern in T1D.
  • Early detection of vascular changes is crucial for risk stratification.

Purpose of the Study:

  • To investigate arterial stiffness in children with T1D.
  • To evaluate the utility of radial artery tonometry for this assessment.

Main Methods:

  • A case-control study involving 98 children with T1D and 57 healthy controls (ages 10-18).
  • Participants were matched for age, sex, race, and BMI.
  • Radial artery tonometry was used to measure augmentation index (AI75).
  • Fasting lipids, HbA1c, glucose, and cytokines were analyzed.

Main Results:

  • Children with T1D exhibited significantly higher augmentation index corrected to heart rate of 75 (AI75) compared to controls.
  • Mean AI75 was 1.11 +/- 10.15 in T1D subjects versus -3.32 +/- 10.36 in controls (P=0.0031).

Conclusions:

  • Children with type 1 diabetes have increased arterial stiffness.
  • Radial artery tonometry is a simple, noninvasive tool for cardiovascular risk stratification in pediatric T1D.
Abstract

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Assessment of radial pulse01:11

Assessment of radial pulse

Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
Assessment of apical radial pulse01:25

Assessment of apical radial pulse

Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Sites for measuring blood pressure01:21

Sites for measuring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement