Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Self-navigated interleaved spiral (SNAILS): application to high-resolution diffusion tensor imaging.

Chunlei Liu1, Roland Bammer, Dong-Hyun Kim

  • 1Lucas MRS/I Center, Department of Radiology, Stanford University, California 94305-5488, USA.

Magnetic Resonance in Medicine
|November 25, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical management of tumor-mimicking posteriorly migrated lumbar disc fragment using a quadrant minimally invasive approach: a case report and literature review.

Frontiers in surgery·2026
Same author

Genesis mechanism of iodide and fluoride in groundwater driven by high-salinity in Bohai Bay.

Journal of contaminant hydrology·2026
Same author

Nitrate pollution sources and associated biogeochemical mechanisms in coastal groundwater affected by seawater intrusion using multiple isotopes and source apportionment models.

Marine pollution bulletin·2026
Same author

A High-Resolution VOC Emission Inventory for Gas Stations in a Typical Yangtze River Delta City: Implications for Ozone Formation, Secondary Organic Aerosol Formation, and Health Risks.

Toxics·2026
Same author

High co-occurrence but low heterogeneity of virulence factors and resistance genes in farmland soil.

Journal of environmental sciences (China)·2026
Same author

Mechanoelectrical metamaterials for broad-range, high-sensitivity pressure sensing.

Science (New York, N.Y.)·2026

This study introduces a novel variable-density spiral imaging technique for diffusion-weighted imaging and diffusion tensor imaging (DTI). The method achieves high-quality brain scans with inherent motion correction, enabling clearer DTI results.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Neuroimaging
  • Medical Physics

Background:

  • Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) are crucial for assessing brain microstructure.
  • Motion artifacts are a significant challenge in MRI, particularly for DTI, leading to signal loss and image distortion.
  • Existing motion correction techniques can be complex and time-consuming.

Purpose of the Study:

  • To implement and evaluate a fat-saturated twice-refocused spin echo sequence with a variable-density (VD) spiral readout for diffusion-weighted imaging (DWI).
  • To develop and assess an iterated motion correction algorithm to further improve image quality by addressing motion-induced phase errors.
  • To demonstrate the feasibility of high-resolution in vivo DTI using the developed VD spiral trajectory.

Main Methods:

Related Experiment Videos

  • A GE Signa 1.5-T MRI system was used with a fat-saturated twice-refocused spin echo sequence.
  • An analytically designed interleaved variable-density (VD) spiral readout trajectory was employed, with center k-space oversampling for inherent motion compensation.
  • An iterated motion correction algorithm was developed, utilizing oversampled k-space data to estimate low-resolution phase maps for artifact reduction.

Main Results:

  • The VD spiral readout produced high-quality diffusion-weighted images with inherent motion compensation, eliminating the need for retrospective correction.
  • The iterated motion correction algorithm effectively reduced signal cancellation artifacts caused by motion-induced phase errors.
  • High-quality isotropic DWI, trace maps, and fractional anisotropy (FA) maps were obtained from in vivo DTI studies of healthy volunteers at 256x256 and, for the first time, 512x512 resolution.

Conclusions:

  • The implemented VD spiral readout trajectory offers a robust and flexible approach for motion-robust DWI and DTI.
  • The combined use of VD spiral readout and iterated motion correction significantly enhances image quality and reduces artifacts in DTI.
  • This technique enables high-resolution in vivo DTI, advancing neuroimaging capabilities.