Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bovine milk allergenicity.

Jean-Michel Wal1

  • 1Laboratoire d'Immuno-Allergie Alimentaire, Service de Pharmacologie et d'Immunologie, Gif sur Yvette, France. wal@cea.fr

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|November 26, 2004
PubMed
Summary

Milk proteins, even at low levels, can be allergens. Epitopes on these proteins, which trigger allergic reactions, vary and are difficult to predict, especially after processing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk assessment of new sequencing information on GM maize event DAS-59122-7.

EFSA journal. European Food Safety Authority·2026
Same author

Scientific Opinion on an application by Dow AgroSciences (EFSA-GMO-NL-2013-116) for placing on the market of genetically modified insect-resistant soybean DAS-81419-2 for food and feed uses, import and processing under Regulation (EC) No 1829/2003.

EFSA journal. European Food Safety Authority·2026
Same author

Scientific Opinion on an application by DOW AgroSciences LLC (EFSA-GMO-NL-2010-89) for placing on the market the genetically modified herbicide-tolerant maize DAS-40278-9 for food and feed uses, import and processing under Regulation (EC) No 1829/2003.

EFSA journal. European Food Safety Authority·2026
Same author

Guidance on allergenicity assessment of genetically modified plants.

EFSA journal. European Food Safety Authority·2020
Same author

Scientific opinion on an application for renewal of authorisation for continued marketing of maize 1507 and derived food and feed submitted under Articles 11 and 23 of Regulation (EC) No 1829/2003 by Pioneer Overseas Corporation and Dow AgroSciences LLC.

EFSA journal. European Food Safety Authority·2020
Same author

Assessment of genetically modified maize GA21 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA-GMO-RX-005).

EFSA journal. European Food Safety Authority·2020

Area of Science:

  • Food allergy research
  • Immunochemistry
  • Protein biochemistry

Background:

  • Milk allergy is a common food allergy.
  • Milk proteins are complex molecules with varying allergenic potentials.

Purpose of the Study:

  • To update knowledge on milk protein allergens.
  • To characterize milk protein epitopes and their role in allergy.

Main Methods:

  • Literature review of clinical, epidemiological, biochemical, and immunochemical data.
  • Expert opinion for data selection.

Main Results:

  • Most milk proteins are potential allergens, regardless of concentration.
  • Allergenic epitopes are conformational and linear, spread across protein molecules.
  • Short, conserved fragments act as IgE cross-reactivity markers and may indicate persistent allergy.

Conclusions:

  • No specific protein structure or function dictates allergenicity.
  • Human IgE response variability prevents identifying a single major allergen.
  • Insufficient data exists to set intake thresholds or predict processing effects on allergenicity.

Related Experiment Videos