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Updated: Aug 20, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Treatment of pediatric obstructive sleep apnea hypopnea syndrome]
Xiao-lan Cai1, Hong-ying Liu, Xian-liang Fan
1Otorhinolaryngology Institute of Health Ministry, Shandong University, Jinan 250012, China. cxlsd@sdu.edu.cn
Insights
Tonsillectomy and adenoidectomy are effective treatments for pediatric obstructive sleep apnea hypopnea syndrome (OSAHS). Transoral endoscopy offers clear visualization and complete removal, significantly improving children's quality of life.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Surgical Oncology
Context:
- Pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) significantly impacts children's health and quality of life.
- Enlarged tonsils and adenoids are common causes of upper airway obstruction in children.
- Effective treatment strategies are crucial for managing pediatric OSAHS.
Purpose:
- To evaluate the effectiveness of surgical interventions, specifically tonsillectomy and/or adenoidectomy, for pediatric OSAHS.
- To assess the curative effects of transoral endoscopy-guided surgery.
- To compare surgical outcomes with other treatment modalities like CPAP and conservative therapy.
Summary:
- A study of 59 pediatric OSAHS patients found tonsillectomy/adenoidectomy effective in 54 cases.
- Transoral endoscopy-guided surgery demonstrated clear visualization and complete removal of obstructing tissues.
- Post-operative follow-up showed significant improvements in quality of life (76.3%), sleep disturbance (88.1%), and physical symptoms (67.8%) with no major complications.
Impact:
- Surgical removal of tonsils and adenoids is a highly effective treatment for pediatric OSAHS.
- Transoral endoscopy enhances surgical precision and patient outcomes.
- Improved quality of life and reduced symptoms in pediatric OSAHS patients following surgical intervention.
Objective:
To evaluate treatment options of pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) and their curative effect.
Methods:
In this study, there are 59 confirmed pediatric obstructive sleep apnea hypopnea syndrome cases diagnosed by polysomnography (PSG). Among them, 54 cases were treated by tonsillectomy or/and adenoidectomy directed by transoral endoscopy. Continue positive airway pressure (CPAP) was used for 2 cases in long-term. Three cases were treated with other conservative therapy. OSA-18 (quality of life for children with obstructive sleep apnea 18 items) was adopted as a disease-specific quality-of-life follow-up survey before and after treatment.
Results:
During perioperation period, no postoperative bleeding or acute respiratory obstruction occurred. Follow-up sleep study was carried out 12-18 months postoperatively, no complications of velopharyngeal insufficiency, nasopharyngeal stenosis or residual adenoid were found. OSA-18 scores showed that quality of life had been significant improved after operation in 76.3% (45 cases), sleep disturbance in 88.1% (52 cases) and physical symptoms in 67.8% (40 cases). The pressure level of long-term CPAP in 2 cases was about 5.6-7.8 cmH2O. 3 cases were slightly improved treated with conservative therapy.
Conclusions:
Surgical removal of upper airway obstruction caused by enlargement of tonsil and adenoid is one of the most effective treatment for pediatric OSAHS. Fibrous endoscopy and cephalometric analysis are helpful to confirm surgical indication. The advantages of transoral endoscopy directed adenoidectomy are as follows: clear and direct visualization, complete removal, without damaging of the peripheral structures.
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