Establishment and maintenance of vascular access in incident hemodialysis patients: a prospective cost analysis
Related Experiment Video
Updated: Aug 20, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Braden Manns1, Marcello Tonelli, Serdar Yilmaz
1Department of Medicine, University of Calgary, Alberta, Canada. Braden.Manns@CalgaryHealthRegion.ca
Insights
Vascular access care significantly impacts hemodialysis costs, with native arteriovenous fistulas being the most cost-effective option. This study highlights the financial benefits of prioritizing fistula placement for hemodialysis patients.
Area of Science:
- Nephrology
- Health Economics
- Vascular Surgery
Background:
- Hemodialysis vascular access is crucial for patient survival.
- The economic burden of vascular access care remains understudied.
- Understanding these costs is vital for optimizing healthcare resource allocation.
Purpose of the Study:
- To conduct a prospective cost analysis of vascular access care in incident hemodialysis patients.
- To determine overall vascular access costs and compare costs across different access types (catheter, arteriovenous fistula, synthetic graft).
Main Methods:
- Prospective cost analysis of 239 incident hemodialysis patients over two years (July 1999 - November 2001).
- Data collection included clinical, demographic, and access type information.
- Comprehensive cost measures encompassed surgery, radiology, hospitalization, physician fees, bacteremia management, and monitoring.
Main Results:
- Vascular access complications accounted for 18.4% of hospital admissions in the first year.
- Mean first-year vascular access care cost was 6890 CAN dollars.
- Cost per patient-year at risk varied significantly: catheter ($9180), arteriovenous fistula ($7989), and synthetic graft ($11,685).
Conclusions:
- Vascular access care represents a substantial portion of initial hemodialysis healthcare expenditures.
- Findings support clinical guidelines advocating for the preferential use of native arteriovenous fistulas due to lower costs and fewer complications.
Abstract:
Despite the importance of hemodialysis vascular access, the cost of vascular access care has not been studied in detail. A prospective cost analysis was performed among incident hemodialysis patients to determine the cost of vascular access care overall and on the basis of access type. Detailed clinical and demographic information, as well as data on access type, was collected for all local incident hemodialysis patients between July 1, 1999, and November 1, 2001. A comprehensive measure of total vascular access costs, including surgery, radiology, hospitalization for access complications, physician costs, costs for management of outpatient bacteremia, and vascular access monitoring costs, was obtained. Costs are reported in 2002 Canadian dollars (1 CAN dollar = 0.69 US dollar). A total of 239 consecutive incident hemodialysis patients were identified, 49, 157, and 33 of whom were dialyzed exclusively with a catheter or had a native arteriovenous fistula or synthetic graft attempted, respectively. In year 1, 18.4% of all hospital admissions were for vascular access-related complications. The mean cost of all vascular access care in year 1 was 6890 CAN dollars(median 4020 dollars; interquartile range [IQR] 2440 dollars to 7540 dollars). The mean cost of access care per patient-year at risk for maintaining a catheter exclusively, attempting an arteriovenous fistula, or attempting a graft was 9180 dollars (median 3812 dollars; IQR 2250 dollars to 7762 dollars), 7989 dollars (median 4641 dollars ; IQR 3035 dollars to 8832 dollars), and 11,685 dollars (median 8152 dollars; IQR 3395 dollars to 12,908 dollars), respectively (P = 0.01). Vascular access care is responsible for a significant proportion of health care costs in the first year of hemodialysis. These results support clinical practice guidelines that recommend preferential placement of a native fistula.
Related Concept Videos
Hemodialysis I: Introduction
Hemodialysis II: Procedure and Complications
Continuous Renal Replacement Therapy
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Acute Kidney Injury V: Interprofessional Care
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
