Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Testis-specific transcriptional control.

S R Grimes1

  • 1Research Service (151), Overton Brooks Veterans Administration Medical Center, Shreveport, LA 71101-4295, USA. srgrimes@prysm.net

Gene
|November 27, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptional control of the testis-specific histone H1t gene.

Gene·2003
Same author

Macro for analysis of CpG and CpNpG methylation in plants.

BioTechniques·2001
Same author

Microsoft Word macro for analysis of cytosine methylation by the bisulfite deamination reaction.

BioTechniques·2001
Same author

Testis-specific histone H1t gene is hypermethylated in nongerminal cells in the mouse.

Biology of reproduction·2000
Same author

Binding of nuclear proteins to an upstream element involved in transcriptional regulation of the testis-specific histone H1t gene.

Journal of cellular biochemistry·1999
Same author

Localization of upstream elements involved in transcriptional regulation of the rat testis-specific histone H1t gene in somatic cells.

Biology of reproduction·1999
Same journal

Genome‑wide identification of the PRN gene family in Rosaceae and the function of PbrPRN2/3 in regulating pollen tube growth.

Gene·2026
Same journal

TBX6 promotes proliferation, invasion, and migration in colorectal cancer: Integrated transcriptomic and protein interaction network analysis.

Gene·2026
Same journal

Face/off: phase-specific modeling of lineage plasticity using near-patient models in genitourinary cancers.

Gene·2026
Same journal

Hierarchical analysis of metabolic phenotype reveals distinct microbiota and circulatory transcriptome in metabolic dysfunction-associated steatotic liver disease.

Gene·2026
Same journal

Mutation T71R enhanced the structural stability and functional activity of wild type superoxide dismutase cloned from soil metagenome.

Gene·2026
Same journal

Reduced ATXN1 expression as an adverse prognostic indicator in Acute myeloid leukemia.

Gene·2026
See all related articles

Testis-specific transcription is crucial for male reproduction, regulating genes in germ cells and supporting cells. The linker histone H1t gene in spermatocytes serves as a model for understanding these complex regulatory mechanisms.

Area of Science:

  • Reproductive biology
  • Molecular genetics
  • Cellular biology

Background:

  • Tissue-specific gene transcription is vital for organism reproduction.
  • Testis-specific genes are essential for spermatogenesis, including proliferation, recombination, meiosis, and differentiation.
  • Understanding these regulatory mechanisms is key to reproductive health.

Purpose of the Study:

  • To describe genes transcribed in male germinal and non-germinal testis cells.
  • To review progress in understanding transcription factors controlling the testis-specific linker histone H1t gene.
  • To utilize the H1t gene as a model for studying testis-specific transcription regulation.

Main Methods:

  • Examination of promoter elements and transcription factors.

Related Experiment Videos

  • Detailed review of studies on the H1t gene in primary spermatocytes.
  • Comparative analysis of gene expression in germinal and non-germinal testis cells.

    • Main Results:

    • Identification of various genes transcribed in different testis cell types.
    • Significant progress in characterizing regulatory elements of the H1t gene.
    • The H1t gene is transcriptionally active in spermatocytes and repressed elsewhere.

    Conclusions:

    • The H1t gene is a valuable model for elucidating testis-specific transcriptional regulation.
    • Regulatory mechanisms controlling H1t gene expression offer insights into broader testis-specific transcription.
    • Further research into these mechanisms can advance understanding of male reproductive processes.