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Related Experiment Videos

Aging and olfactory and taste function.

Kristin A Seiberling1, David B Conley

  • 1Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, 675 North St. Claire Street, Chicago, IL 60611, USA.

Otolaryngologic Clinics of North America
|November 27, 2004
PubMed
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Aging significantly impacts smell and taste, leading to chemosensory dysfunction in the elderly. This review covers causes, evaluation, consequences, and treatments for these age-related sensory changes.

Area of Science:

  • Gerontology
  • Neuroscience
  • Sensory Science

Background:

  • Olfaction and taste (chemosensation) undergo significant changes with aging.
  • Age-related decline in chemosensory function is common in the elderly population.
  • These changes can impact nutrition, quality of life, and safety.

Purpose of the Study:

  • To provide a comprehensive overview of age-related changes in olfaction and taste.
  • To discuss the causes and clinical consequences of chemosensory dysfunction in older adults.
  • To outline evaluation methods, diagnostic tools, and treatment strategies for impaired smell and taste.

Main Methods:

  • Review of literature on aging, olfaction, taste, and chemosensory disorders.
  • Emphasis on histopathological changes associated with aging in sensory organs.

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  • Discussion of clinical evaluation, diagnostic tests, and imaging modalities.

    • Main Results:

    • Age-related histopathological changes affect the structures responsible for smell and taste.
    • Numerous factors contribute to chemosensory dysfunction in the elderly, including diseases and medications.
    • Chemosensory impairments have significant clinical consequences, such as malnutrition and increased risk of hazards.

    Conclusions:

    • Age-related decline in olfaction and taste is a complex issue with multifactorial causes.
    • Systematic evaluation and appropriate interventions can manage chemosensory dysfunction.
    • Addressing these sensory changes is crucial for maintaining health and well-being in aging individuals.