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Kentucky's first liver transplant program.

F R Bentley1, R N Garrison, J D Richardson

  • 1Department of Surgery, University of Louisville School of Medicine, KY 40292.

The Journal of the Kentucky Medical Association
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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This study evaluated liver transplant outcomes, finding that 11 of 16 recipients are alive and well, with most returning to normal life. Patient selection and post-transplant care are crucial for successful orthotopic liver transplantation.

Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Immunology

Background:

  • Orthotopic liver transplantation is a life-saving procedure for end-stage liver disease.
  • Patient selection and post-transplant management significantly impact outcomes.
  • The early experience of a liver transplant program provides valuable insights.

Purpose of the Study:

  • To evaluate the outcomes of orthotopic liver transplantation at a single institution.
  • To assess patient survival and quality of life post-transplantation.
  • To identify factors influencing transplant success.

Main Methods:

  • Retrospective review of 49 referred patients for orthotopic liver transplantation.
  • Analysis of patient selection, waiting list mortality, and post-transplant outcomes.

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  • Follow-up of recipients for survival and return to normal activity.

    • Main Results:

    • 16 patients underwent liver transplantation.
    • 11 recipients (69%) are alive and well post-transplant, with 9 returning to normal activity.
    • 8 patients died awaiting a donor, and 5 died post-transplant.

    Conclusions:

    • Orthotopic liver transplantation can achieve favorable outcomes with careful patient selection and management.
    • Successful transplantation leads to improved quality of life for recipients.
    • Ongoing evaluation and management are essential for long-term success.