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Determinants of white-coat hypertension
1ADAPT Centre, Beaumont Hospital, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, Ireland.
Insights
White-coat hypertension (WCH), a condition of elevated office blood pressure, affects 15.4% of patients. Older adults, females, and non-smokers are more likely to have WCH.
Area of Science:
- Cardiology
- Hypertension Research
Background:
- White-coat hypertension (WCH) is frequently observed in patients with elevated office blood pressure.
- Misdiagnosis of WCH can lead to unnecessary antihypertensive medication use.
- Understanding WCH patient profiles is crucial for accurate diagnosis and treatment.
Framework:
- Study included 5716 patients referred over 22 years.
- Defined WCH as clinic BP > 140/90 mmHg with normal daytime ambulatory BP.
- Collected baseline clinic and daytime ambulatory blood pressure data.
Implementation:
- Prevalence of WCH was determined to be 15.4%.
- Identified higher WCH prevalence in older adults, females, and non-smokers.
- Utilized multivariate logistic regression to analyze predictors.
Implications:
- Identified key demographic and lifestyle factors associated with WCH.
- Findings aid in identifying patients at higher risk for WCH.
- Supports targeted ambulatory blood pressure monitoring for at-risk individuals.
Background:
The prevalence of white-coat hypertension (WCH) is considerable in patients referred with elevated office blood pressure. Failure to recognise this phenomenon can lead to the inappropriate use of antihypertensive medications. We undertook this study to determine the profile of patients with WCH.
Methods:
Baseline clinic and daytime ambulatory blood pressures were available from 5716 patients referred over a 22-year period. Individuals were considered to have WCH if they had an elevated clinic blood pressure measurement greater than 140/90 mmHg and normal daytime mean ambulatory blood pressure. Mean age was 53.6 years and 53.2% were female.
Results:
The overall prevalence of white-coat hypertension was 15.4%. A higher prevalence was seen amongst older adults, females, and non-smokers.
Conclusion:
Multivariate logistic regression analysis confirmed these characteristics as independent predictors of WCH.
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