Related Experiment Video
Updated: Aug 20, 2026

An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
Published on: December 1, 2017
Work-site-based influenza vaccination in healthcare and non-healthcare settings
Sarah J D'Heilly1, Kristin L Nichol
1Medicine Service and Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minnesota 55417, USA.
Objective:
To better understand work-site-based programs for influenza vaccination.
Design:
Self-administered, mailed questionnaire.
Setting:
Healthcare and non-healthcare companies.
Participants:
Random sample of 2000 members of the American Association of Occupational Health Nurses.
Results:
The response rate was 55%, and 88% of the respondents were employed by companies sponsoring work-site influenza vaccination. Thirty-two percent of respondents worked for healthcare and healthcare-related services companies. Healthcare companies were more likely to sponsor worksite-based vaccination (94% vs 85%; P < .0001) compared with non-healthcare companies. Healthcare companies were also more likely to encourage vaccination of high-risk employees (70% vs 55%; P < .0001) and cover its cost (86% vs 61%; P < .0001). Multivariate logistic regression was used to determine factors associated with highly successful vaccination. Being a healthcare-related company (OR, 2.1; CI95, 1.4-3.2; P < .0001), employers covering the vaccination cost (OR, 3.1; CI95, 1.4-6.6; P = .004), having more experience with work-site vaccination (OR, 1.6; CI95, 1.0-2.4; P = .036), and management encouraging vaccination (OR, 2.6; CI95, 1.4-4.9; P = .002) were associated with highly successful programs.
Conclusions:
Most of the occupational health nurses surveyed work for employers sponsoring work-site vaccination, and 32% were employed by healthcare and related services companies. Healthcare companies were more likely to sponsor worksite-based vaccination and to vaccinate most of their employees; however, only 18% had vaccination rates higher than 50%. Strategies need to be developed to increase vaccination rates so that benefits of vaccination can be realized by employers and employees.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
PPE Use in Healthcare Settings I: Donning
Influenza
Preventive Healthcare Services

