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Related Experiment Videos

Depression and diabetes symptom burden.

Evette J Ludman1, Wayne Katon, Joan Russo

  • 1Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA. ludman.e@ghc.org

General Hospital Psychiatry
|November 30, 2004
PubMed
Summary

Major depression significantly increases the number of diabetes symptoms reported by patients. This association between depression and diabetes symptoms is stronger than links to glycemic control or complications.

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Area of Science:

  • Endocrinology
  • Psychiatry
  • Primary Care

Background:

  • Diabetes mellitus is a chronic condition requiring ongoing management.
  • Depressive illness is a common comorbidity in patients with diabetes.
  • Patient-reported symptoms and objective measures are crucial for comprehensive diabetes care.

Purpose of the Study:

  • To investigate the relationship between patient-reported diabetes symptoms, depressive illness severity, and objective diabetes control measures.
  • To assess the association between depression and specific diabetes symptoms.
  • To compare the strength of the depression-diabetes symptom association with glycemic control and complication associations.

Main Methods:

  • A population-based sample of 4168 patients with diabetes from nine primary care clinics participated.

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  • Surveys assessed major depression using the Patient Health Questionnaire (PHQ-9) and diabetes symptoms.
  • Automated medical records provided data on HbA1c, complications, and comorbidities.

    • Main Results:

    • Patients with major depression reported significantly more diabetes symptoms (mean=4.40) than those without depression (mean=2.46).
    • The number of diabetes symptoms was strongly related to the number of depressive symptoms.
    • Depression was significantly associated with all ten individual diabetes symptoms (P<.001).

    Conclusions:

    • The association between depression and diabetes symptoms is more pronounced than the link between diabetes symptoms and glycemic control or complications.
    • Depression significantly impacts the experience of diabetes symptoms in patients.
    • Clinical attention to depression is vital for managing diabetes symptom burden.