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A new flavan from Daphne odora var. atrocaulis
Wei Zhang1, WeiDong Zhang, TingZhao Li
1Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China.
Fitoterapia
|November 30, 2004
Summary
A novel flavan compound, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), was successfully isolated from the roots of Daphne odora var. atrocaulis. This discovery expands the known chemical constituents of this plant species.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Plant Sciences
Background:
- Daphne odora var. atrocaulis is a plant species with a history of traditional use.
- The chemical composition of Daphne species is of interest for potential bioactive compounds.
Purpose of the Study:
- To report the isolation and identification of a new chemical compound from Daphne odora var. atrocaulis.
- To characterize the structure of the newly discovered flavan.
Main Methods:
- Phytochemical investigation of Daphne odora var. atrocaulis root extract.
- Isolation and purification techniques (e.g., chromatography).
- Structure elucidation using spectroscopic methods (e.g., NMR, MS).
Main Results:
- Isolation of a new flavan, designated as 5,7,4 '-trihydroxy-8-ethoxycarbonylflavan (1).
- Confirmation of the structure of compound 1 through detailed spectroscopic analysis.
- Identification of the source as the root of Daphne odora var. atrocaulis.
Conclusions:
- The study successfully identified a novel flavan from Daphne odora var. atrocaulis.
- The discovery of 5,7,4 '-trihydroxy-8-ethoxycarbonylflavan contributes to the understanding of Daphne species' phytochemistry.