Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The effect on anterior column loading due to different vertebral augmentation techniques.

Dheera Ananthakrishnan1, Sigurd Berven, Vedat Deviren

  • 1Orthopaedic Biomechanics Laboratory, San Francisco General Hospital, University of California, 1001 Potrero Ave., #3A36, San Francisco, CA 94110, USA.

Clinical Biomechanics (Bristol, Avon)
|November 30, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Strategy for Simultaneous Multiomic Survey of N-Glycomic and Extracellular Matrix Proteome by Mass Spectrometry Imaging.

Journal of the American Society for Mass Spectrometry·2026
Same author

Correction: ISSLS Prize in Clinical Science 2026: Data-driven classification of lumbar spine degeneration trajectories in chronic low back pain.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
Same author

Comparison of key diagnostics for probabilistic interpretation of STR mixture data generated with length-based and MPS methodologies.

Forensic science international. Genetics·2026
Same author

Celebrating ISSLS Science, Leadership, Legacy, and Partnership with the European Spine Journal.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
Same author

Dual Roles of Voltage-gated Calcium Channels and γ-Aminobutyric Acid-mediated Signaling in Modulating Neurotensin Receptor Type 2-induced Antinociception.

Anesthesiology·2026
Same author

Vertebral endplate bone marrow lesion composition: relation to Modic change classification and associations with chronic low back pain.

The spine journal : official journal of the North American Spine Society·2026

Vertebroplasty and kyphoplasty treatments for vertebral compression fractures minimally restore spinal loading. Neither procedure fully restores disc pressure to pre-fracture levels, suggesting adjacent fractures result from disease progression, not the intervention.

Area of Science:

  • Orthopedics
  • Spinal Surgery
  • Biomechanics

Background:

  • Vertebral compression fractures cause significant morbidity in the elderly, including pain and reduced mobility.
  • Vertebroplasty and kyphoplasty are common treatments, but their effect on spinal loading is unclear.

Purpose of the Study:

  • To compare the effectiveness of vertebroplasty and kyphoplasty in restoring spinal loading after vertebral compression fractures.

Main Methods:

  • A cadaveric thoracolumbar spine model was fractured and treated with either vertebroplasty or kyphoplasty.
  • Three loading regimes were applied to intact, fractured, and treated spines.
  • Sub-adjacent disc nuclear pressure was measured to assess anterior column loading.

Main Results:

Related Experiment Videos

  • Fracture significantly reduced nuclear pressure; treatments only minimally increased it, not to pre-fracture levels.
  • No significant differences in nuclear pressure restoration were observed between vertebroplasty and kyphoplasty.
  • Both treatments allowed for increased disc pressure generation compared to the fractured state.

Conclusions:

  • Neither vertebroplasty nor kyphoplasty fully restores nucleus pulposus pressure to intact levels.
  • Adjacent segment fractures after these treatments are likely due to disease progression, not the procedures themselves.