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[Expression of macrophage migration inhibition factor in pancreatic carcinoma tissue]
Zhi-qing Jin1, Fa-chao Zhi, Xue-qing Chen
1Institute for Digestive Disease of PLA, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. potatoneimeng@163.com
Objective:
To observe the expression of macrophage migration inhibitory factor (MIF) in pancreatic carcinoma tissue and analyze the relationship between MIF expression and clinical manifestations.
Methods:
MIF expression in pancreatic carcinoma and normal pancreatic tissue were detected with immunohistochemical method.
Result:
The positivity rates of MIF in pancreatic carcinoma and normal pancreatic tissue were 69.4% (25/36) and 0 (0/10) respectively. MIF expression was found to relate to the degree of cell differentiation of pancreatic carcinoma, but not to the clinical stages or the status of lymph node metastasis.
Conclusion:
MIF might be related to the pathogenesis of pancreatic carcinoma.
