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[Sleep disorders in multiple sclerosis].

R Alarcia1, J R Ara, J Martín

  • 1Servicio de Neurologia,Unidad de Enfermedades Desmielinizantes, Hospital Universitario Miguel Servet, Zaragoza. lcarmen@comz.org

Neurologia (Barcelona, Spain)
|November 30, 2004
PubMed
Summary
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Sleep disorders affect 36% of multiple sclerosis (MS) patients. Depression is the only independent factor linked to sleep disturbances in MS, increasing their likelihood by 1.2 times per point on the Hamilton scale.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Psychiatry

Context:

  • Multiple sclerosis (MS) is a chronic neurological disease affecting the central nervous system.
  • Sleep disorders are common in MS patients but their specific relationship with disease manifestations requires further investigation.
  • Understanding these relationships is crucial for improving patient quality of life.

Purpose:

  • To investigate the prevalence of sleep disorders in patients with multiple sclerosis.
  • To examine the association between sleep disorders and other clinical manifestations of MS, including disability and depression.
  • To identify independent predictors of sleep disorders in the MS population.

Summary:

  • This study evaluated 100 patients with clinically definite multiple sclerosis (MS), assessing sleep quality, depression, disability, and fatigue.

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  • The prevalence of sleep disorders was found to be 36%.
  • Logistic regression analysis revealed that depression, measured by the Hamilton Depression Rating Scale, was the sole independent predictor of sleep disorders in MS patients, with each additional point increasing the odds by 1.2.

    • Impact:

    • Identifies depression as a key factor associated with sleep disorders in multiple sclerosis patients.
    • Highlights the need for screening and managing depression to address sleep disturbances in MS care.
    • Provides valuable insights for clinicians managing patients with multiple sclerosis and sleep-related issues.