Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Six new diterpenoids from Suregada multiflora.

Ismet Ara Jahan1, Nilufar Nahar, M Mosihuzzaman

  • 1Department of Chemistry, University of Dhaka, Dhaka-1000, Bangladesh.

Journal of Natural Products
|December 1, 2004
PubMed
Summary

Six new diterpenoids, including novel diterpene lactones and kaurane derivatives, were isolated from Suregada multiflora bark. These compounds possess unique structural features, such as cyclopropane rings and seven-membered rings, expanding the known chemical diversity of natural products.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glycoprotein Hydrogen-Bonding Hypothesis and Its Relationship with Other Mechanisms of Molecular Memory.

Current medicinal chemistry·2026
Same author

Quantum Consciousness: A Molecular Perspective Involving Glycoprotein-Tunnelling Hypothesis (GPTH).

Current medicinal chemistry·2026
Same author

Synergistic Potential of Organotin(IV) Carbodithioate Derivatives with Vitamins D and E in MCF-7 and MDA-MB-231 Breast Cancer Cells.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Multitarget synthetic piperates against key drug targets of Alzheimer's and diabetes mellitus.

RSC advances·2026
Same author

The Effects of Vitamin D on the Breast Cancer Tumor Microenvironment.

Cancers·2025
Same author

Synthesis and pharmacological profiling of cis-1-amino-2-indanol derivatives as α-glucosidase inhibitors.

Scientific reports·2025

Area of Science:

  • Natural Product Chemistry
  • Organic Chemistry
  • Phytochemistry

Background:

  • Suregada multiflora is a plant species known to produce various secondary metabolites.
  • Diterpenoids represent a diverse class of natural products with a wide range of biological activities.
  • Investigating the chemical constituents of medicinal plants can lead to the discovery of novel compounds.

Purpose of the Study:

  • To isolate and characterize new diterpenoids from the bark of Suregada multiflora.
  • To elucidate the chemical structures of these novel compounds using spectroscopic methods.
  • To contribute to the understanding of the phytochemical diversity of the Suregada genus.

Main Methods:

  • Extraction of plant material using dichloromethane-methanol solvent mixture.

Related Experiment Videos

  • Isolation of compounds using chromatographic techniques.
  • Structure elucidation through one- and two-dimensional Nuclear Magnetic Resonance (NMR) spectroscopy, mass spectrometry, and chemical derivatization.

    • Main Results:

    • Isolation of six new diterpenoids: suregadolides C (1) and D (2), suremulide A (3), bannaringaolide A (4), suremulol A (5), and suremulol B (6).
    • Suregadolides C and D are new diterpene lactones with a cyclopropane ring on an abietane skeleton.
    • Bannaringaolide A features a novel diterpene lactone skeleton with a seven-membered ring, potentially derived from an ent-pimarane framework.

    Conclusions:

    • The study successfully identified six novel diterpenoids from Suregada multiflora bark.
    • The isolated compounds exhibit unique and complex structural features, expanding the known chemical diversity of diterpenoids.
    • These findings provide valuable insights into the biosynthesis and chemotaxonomy of natural products from this plant species.