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Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Microscopically controlled excision of skin cancer
J K Lim1, M M Stewart, D G Pennington
1Royal Prince Alfred Hospital, Camperdown, NSW.
The Medical Journal of Australia
|April 6, 1992
Summary
Microscopically controlled excision, also known as Mohs surgery, achieved a 97.1% cure rate for skin cancer. This technique is particularly effective for challenging basal cell carcinomas, offering superior results compared to traditional methods.
Area of Science:
- Dermatology
- Surgical Oncology
Background:
- Skin cancer treatment requires precise surgical techniques.
- Mohs surgery offers microscopic control during excision.
- Early adoption of Mohs surgery was evaluated at Royal Prince Alfred Hospital.
Purpose of the Study:
- To detail the microscopically controlled excision technique (Mohs surgery).
- To review the initial outcomes of Mohs surgery at Royal Prince Alfred Hospital.
Main Methods:
- Retrospective review of 170 skin cancer cases treated between 1981-1983.
- Analysis of 148 patients with 170 lesions undergoing long-term follow-up.
- Evaluation of patient demographics, lesion characteristics, and surgical procedure details.
Main Results:
- An overall cure rate of 97.1% was achieved.
- The cure rate is comparable to established centers performing Mohs surgery.
- Average procedure involved 2.1 excision stages and 14.8 frozen sections per tumor.
Conclusions:
- Microscopically controlled excision provides an excellent cure rate for skin cancers.
- The technique is highly effective for recurrent or difficult basal cell carcinomas, especially in high-risk facial areas.
- Selected application of Mohs surgery yields higher cure rates than conventional treatments.
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