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Updated: Aug 20, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
MACAT--microarray chromosome analysis tool
Joern Toedling1, Sebastian Schmeier, Matthias Heinig
1Freie Universitaet Berlin, Bioinformatics programme and Max Planck Institute for Molecular Genetics, Germany.
Unlabelled:
By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions. We demonstrate the applicability of the approach on a publicly available data set on acute lymphocytic leukemia.
Availability:
The R-package MACAT can be obtained from http://www.compdiag.molgen.mpg.de/software/macat.shtml
Supplementary Information:
http://www.compdiag.molgen.mpg.de/software/macat.shtml.
