Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dextromethorphan abuse.

Edward W Boyer1

  • 1Division of Medical Toxicology, University of Massachusetts Medical School, USA. edward.boyer@tch.harvard.edu

Pediatric Emergency Care
|December 2, 2004
PubMed
Summary
This summary is machine-generated.

Dextromethorphan (DXM) is a popular drug of abuse among adolescents, causing varied toxicities. Early identification and treatment are crucial to prevent further substance abuse in this population.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PrEPSteps: A Pilot Randomized Controlled Trial to Assess the Feasibility and Acceptability of a Digital Pill-Based PrEP Adherence Intervention in Men Who Have Sex with Men with Substance Use Disorder.

AIDS and behavior·2026
Same author

Clinically characterizing adults who use kava or kratom: Substance use disorder assessment challenges for increasingly popular botanical products.

Drug and alcohol dependence reports·2025
Same author

Substance Use Disorder Following Consumption of a Novel Synthetic 7-Hydroxymitragynine Product.

Journal of addiction medicine·2025
Same author

Complicating Factors Surrounding Concurrent Use of Kratom and a Novel 7-hydroxymitragynine Product Among a Participant Enrolled in a Kratom Clinical Trial.

Journal of addiction medicine·2025
Same author

Pneumonia Diagnosis Agreement Between Treating Emergency Physicians and Adjudicators in Older Adult Emergency Department Patients.

Journal of the American College of Emergency Physicians open·2025
Same author

De facto opioids: Characterization of novel 7-hydroxymitragynine and mitragynine pseudoindoxyl product marketing.

Drug and alcohol dependence·2025
Same journal

Pediatric E-Scooter and Traditional Scooter Injuries: Emergency Department Visits 2015-2024.

Pediatric emergency care·2026
Same journal

Performance and Yield of Retinal Examinations in Cases of Suspected Physical Abuse Without Intracranial Injury.

Pediatric emergency care·2026
Same journal

Using Quality Improvement Methodology to Inform Safe Implementation of Propofol Procedural Sedation in a Pediatric Emergency Department.

Pediatric emergency care·2026
Same journal

Response to Ortiz-Santiago et al: Reasons for Ordering a Computed Tomography Scan and Abnormalities Found in Pediatric Intermediate-Risk Mild Head Trauma.

Pediatric emergency care·2026
Same journal

Response to Ortiz-Santiago et al, "Reasons for Ordering a Computed Tomography Scan and Abnormalities Found in Pediatric Intermediate-Risk Mild Head Trauma".

Pediatric emergency care·2026
Same journal

Improving Emergency Care for Children With Medical Complexity: A Pragmatic Review.

Pediatric emergency care·2026
See all related articles

Area of Science:

  • Pharmacology
  • Toxicology
  • Adolescent Medicine

Background:

  • Dextromethorphan (DXM) is an accessible over-the-counter cough suppressant.
  • Increasing popularity of DXM as a recreational drug among adolescents.
  • DXM acts as a dissociative agent with potential for abuse.

Observation:

  • DXM abuse leads to a spectrum of toxicities, dose-dependent.
  • Formulation components can influence the type and severity of toxicity.
  • Most cases of DXM intoxication are managed with supportive care.
  • Severe intoxication necessitates significant medical intervention.

Findings:

  • Adolescent misuse of DXM is a growing concern.
  • Toxic effects vary based on dosage and specific product ingested.

Related Experiment Videos

  • Supportive care is often sufficient for mild to moderate intoxication.
  • Severe cases require prompt medical attention and management.

    • Implications:

    • Early recognition of DXM abuse is vital in pediatric populations.
    • Effective treatment and referral can mitigate risks of broader substance abuse.
    • Clinicians must be prepared to identify, manage, and refer adolescent DXM intoxication.
    • Understanding DXM toxicity is key for public health interventions targeting youth.