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Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
Published on: June 28, 2019
Epoxy-based production of wind turbine rotor blades: occupational contact allergies
Ann Pontén1, Ole Carstensen, Kurt Rasmussen
1Department of Occupational and Environmental Dermatology, Malmö University Hospital, Malmö, Sweden. ann.ponten@skane.se
Background:
An industry producing rotor blades for wind turbines with an epoxy-based technology had experienced an increasing number of workers with dermatitis, among whom the frequency of occupational contact allergy (OCA) was suspected to be underestimated.
Objective:
To investigate the frequency of OCA by patch-testing with a specially profiled occupational patch test series.
Methods:
In a blinded study design, 603 workers were first interviewed and thereafter clinically examined. Based on a history of work-related skin disease, clinical findings of dermatitis, or both, 325 (53.9%) of the workers were patch-tested with an occupational patch test series and the European Standard patch test series.
Results:
Of the 603 investigated workers, 10.9% had OCA and 5.6% had contact allergy to epoxy resin in the standard test series. Contact allergy to amine hardeners/catalysts was found in 4.1% of the workers. Among the workers with OCA, 48.5% reacted to work material other than epoxy resin in the European Standard patch test series.
Conclusion:
Approximately 50% of the workers with OCA would not have been detected if only the European Standard patch test series had been used.
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