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Related Experiment Videos

Microsensors and microbiosensors for retinal implants.

David D Zhou1, Robert J Greenberg

  • 1Second Sight Medical Products, Inc., Sylmar Biomedical Park, 12744 San Fernando Road, Bldg.3, Sylmar, California 91342, USA. dmzhou@2-sight.com <dmzhou@2-sight.com>

Frontiers in Bioscience : a Journal and Virtual Library
|December 3, 2004
PubMed
Summary

Recent advances in microsensors and microbiosensors are explored for visual prostheses, focusing on implantable sensors for pH, glucose, and L-glutamate monitoring in retinal prosthetic devices.

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Area of Science:

  • Biomedical Engineering
  • Sensor Technology
  • Neuroscience

Background:

  • Visual prostheses aim to restore sight by interfacing with the visual system.
  • Retinal prosthetic devices require sophisticated sensing capabilities for optimal function.
  • In-vivo monitoring of physiological parameters is crucial for understanding and treating visual impairments.

Purpose of the Study:

  • To review recent developments in microsensors and microbiosensors for visual prostheses.
  • To highlight the importance of in-vivo pH measurements and implantable pH sensors.
  • To discuss electrochemical biosensors for glucose and L-glutamate detection in the retina.

Main Methods:

  • Review of electrochemical biosensors for neurotransmitter and metabolite detection.

Related Experiment Videos

  • Exploration of novel electrode materials, including thin-film diamond.
  • Discussion of microelectromechanical systems (MEMS) technology for implantable devices.

    • Main Results:

    • Chemically modified thin-film diamond shows promise for implantable biosensors.
    • Electrochemical biosensors enable sensitive measurements of glucose and L-glutamate.
    • Development of microsensors and microbiosensors is advancing retinal prosthetic applications.

    Conclusions:

    • Microsensors and microbiosensors are critical for the advancement of visual prostheses.
    • Implantable sensors for pH, glucose, and L-glutamate are essential for retinal prosthetic devices.
    • Overcoming challenges in chronic implantable sensor systems is key for future success.