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Updated: Aug 18, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
Published on: October 22, 2012
Immune peptide enhancement of peptide based vaccines
1Northeastern Ohio Universities College of Medicine, 4209 SR 44, Rootstown, OH 44272, USA. ksr@neoucom.edu <ksr@neoucom.edu>
Abstract:
Vaccines optimize the presentation of an immunogen to the immune system, oftentimes enhancing or replacing the natural activators of antigen presenting cells in order to promote the delivery and the response of T and B lymphocytes to the immunogen. The purpose of this series is to describe new technologies which allow vaccine design, based on our understanding of the immune response, using different approaches to immune peptide enhancement of peptide based vaccines. In this introduction to the series entitled, "Immune Peptide Enhancement of Peptide Based Vaccines", some of the immunological concepts relevant to vaccine design are presented.
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