Related Experiment Videos

Pharmacotherapy and blood pressure control in elderly hypertensives in a primary care setting in Bahrain

Khalid A Jassim Al Khaja1, Reginald P Sequeira, Awatif H H Damanhori

  • 1Department of Pharmacology and Therapeutics, College of Medicine and Medical Sciences, Arabian Gulf University, Kingdom of Bahrain. khlidj@agu.edu.bh

Insights

Optimal blood pressure control in elderly hypertensives remains a challenge, with few achieving guideline targets. Physician adherence to hypertension management guidelines in primary care requires improvement for better patient outcomes.

Area of Science:

  • Cardiology
  • Geriatrics
  • Pharmacology

Background:

  • Antihypertensive treatment in the elderly significantly reduces cardiovascular risks.
  • Current primary care practices in Bahrain were evaluated for adherence to hypertension management guidelines.

Purpose of the Study:

  • To assess primary care physician adherence to World Health Organization/International Society of Hypertension (WHO/ISH) guidelines for antihypertensive drug management in elderly patients.
  • To determine the extent of blood pressure (BP) control achieved in this population.

Main Methods:

  • A multicentric therapeutic audit of medical records was conducted.
  • Data from elderly hypertensive patients (>= 60 years) in nine primary care centers in Bahrain were analyzed.

Main Results:

  • Only 11.1% of elderly hypertensives and 4.1% of elderly diabetic hypertensives met WHO/ISH-1999 BP targets (<140/90 mmHg or <130/85 mmHg for diabetics).
  • Combination therapy was used in about half of patients, with no significant BP difference compared to monotherapy.
  • Beta-blockers were most prescribed overall, ACE inhibitors in diabetics, while preferred diuretics and calcium channel blockers were underutilized, especially in isolated systolic hypertension.

Conclusions:

  • Suboptimal drug management and poor adherence to guidelines were observed in elderly hypertensive patients.
  • Comorbidities like diabetes influenced antihypertensive choices, but overall therapy tailoring was inadequate.
  • Improved drug management strategies are needed in primary care for elderly hypertensive patients.
Abstract

Related Concept Videos

Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...