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Pharmacotherapy and blood pressure control in elderly hypertensives in a primary care setting in Bahrain
Khalid A Jassim Al Khaja1, Reginald P Sequeira, Awatif H H Damanhori
1Department of Pharmacology and Therapeutics, College of Medicine and Medical Sciences, Arabian Gulf University, Kingdom of Bahrain. khlidj@agu.edu.bh
Insights
Optimal blood pressure control in elderly hypertensives remains a challenge, with few achieving guideline targets. Physician adherence to hypertension management guidelines in primary care requires improvement for better patient outcomes.
Area of Science:
- Cardiology
- Geriatrics
- Pharmacology
Background:
- Antihypertensive treatment in the elderly significantly reduces cardiovascular risks.
- Current primary care practices in Bahrain were evaluated for adherence to hypertension management guidelines.
Purpose of the Study:
- To assess primary care physician adherence to World Health Organization/International Society of Hypertension (WHO/ISH) guidelines for antihypertensive drug management in elderly patients.
- To determine the extent of blood pressure (BP) control achieved in this population.
Main Methods:
- A multicentric therapeutic audit of medical records was conducted.
- Data from elderly hypertensive patients (>= 60 years) in nine primary care centers in Bahrain were analyzed.
Main Results:
- Only 11.1% of elderly hypertensives and 4.1% of elderly diabetic hypertensives met WHO/ISH-1999 BP targets (<140/90 mmHg or <130/85 mmHg for diabetics).
- Combination therapy was used in about half of patients, with no significant BP difference compared to monotherapy.
- Beta-blockers were most prescribed overall, ACE inhibitors in diabetics, while preferred diuretics and calcium channel blockers were underutilized, especially in isolated systolic hypertension.
Conclusions:
- Suboptimal drug management and poor adherence to guidelines were observed in elderly hypertensive patients.
- Comorbidities like diabetes influenced antihypertensive choices, but overall therapy tailoring was inadequate.
- Improved drug management strategies are needed in primary care for elderly hypertensive patients.
Background And Aims:
Antihypertensive treatment in the elderly has important beneficial effects in terms of reduced cardiovascular morbidity and mortality. The aim of this study was to determine, in elderly hypertensives, the adherence of primary care physicians to World Health Organization/International Society of Hypertension (WHO/ISH) guidelines for the drug management of hypertension and extent of blood pressure (BP) control.
Methods:
A multicentric therapeutic audit of medical records of elderly hypertensives was performed in nine primary care health centers in the Kingdom of Bahrain.
Results:
In elderly hypertensives (> or =60 years), the WHO/ISH-1999 recommended BP targets of <140/<90 mmHg and BP<130/85 mmHg were achieved in 11.1% of elderly hypertensives and 4.1% of elderly diabetic hypertensives, respectively. Antihypertensive combination therapy was used in approximately half of the elderly. No significant difference in BP was found in elderly hypertensives treated either with monotherapy or combination therapy. As regards mono- and overall drug utilization, beta-blockers were the most frequently prescribed drugs in hypertensives, and angiotensin-converting enzyme (ACE) inhibitors in diabetic hypertensives. Diuretics and calcium channel blockers, the preferred antihypertensives for the elderly, were less often prescribed, particularly in patients with isolated systolic hypertension.
Conclusions:
Approximately one out of 9 elderly hypertensives and one out of 24 diabetic hypertensives achieved optimal BP control. Although preference for antihypertensives was markedly influenced by comorbidity with diabetes, tailoring of drug therapy was suboptimal and did not adhere to the recommended guidelines in elderly hypertensives. Efforts to improve the drug management of hypertension at primary care level, particularly in the elderly, are required.
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