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[Study on the compatibility of composite herbal medicines of the Zishen pill]
Rong-hua Dai1, Yuan-yuan Zhang, Kai-shun Bi
1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Objective:
To study the compatibility of composite herbal medicines of the Zishen pill.
Method:
50% ethanol extract test solution of the different combinations of composite herbal medicines of the Zishen pill were prepared. Pharmacologic experiments, such as anti-inflammatory, carbon particle clearance of RES were carried out with the solutions, and the corresponding pharmacological data were obtained. Variance analysis, canonical correlation and stepwise regression analysis were applied to interrelate the amount of each drug and the pharmacological data.
Result:
The results confirmed that Huangbo and Zhimu were the basis, while Rougui was the corrigent, which was conformed to the theory of TCM.
Conclusion:
This study provides a significant try for studying the compatibility of composite herbal medicines.
