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The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing

Bing-Bing Wang1, Volker Brendel

  • 1Department of Genetics, Development and Cell Biology Iowa State University, Ames, IA 50011-3260, USA. icewater@iastate.edu <icewater@iastate.edu>

Genome Biology
|December 4, 2004
PubMed

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Alternative RNA Splicing02:18

Alternative RNA Splicing

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Alternative RNA Splicing02:18

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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl guanosine). This 5’ cap helps the...
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