[Mechanism of vascular calcification]
Related Experiment Video
Updated: Aug 20, 2026

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models
Published on: January 27, 2023
1Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Abstract:
Vascular calcification, especially in coronary artery not only serves as a surrogate marker for atherosclerosis, but also predicts a higher risk of myocardial infarction and death. Its pathogenesis involves an active mineralization process by chondrogenic and osteogenic cells as well as a passive precipitation of minerals. Since atherosclerosis is a chronic vascular inflammation, plaque calcification is conceptualized as a chondrogenic and/or osteogenic process associated with chronic vascular inflammation.
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