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Hypoplasia of urinary bladder
J H Meriwether1, R Witherington
1Section of Urology, Medical College of Georgia School of Medicine, Augusta.
Insights
This study details three female patients with bladder hypoplasia, a rare congenital condition. Early intervention with cutaneous ureterostomy led to survival into adulthood, with some receiving kidney transplants.
Area of Science:
- Pediatric Urology
- Congenital Anomalies
- Nephrology
Background:
- Bladder hypoplasia is a rare congenital anomaly.
- Associated congenital anomalies can complicate management.
- Obstructive uropathy is a common presentation in affected infants.
Observation:
- Three female patients with bladder hypoplasia were identified.
- All presented in early infancy with significant obstructive uropathy.
- Management involved early loop cutaneous ureterostomy.
Findings:
- All patients survived to adulthood.
- Two patients received kidney transplants into an ileal conduit.
- One patient maintained good health with cutaneous ureterostomy alone.
Implications:
- Early ureterostomy is a viable management strategy for bladder hypoplasia.
- Long-term outcomes can be favorable, including successful kidney transplantation.
- Understanding pathogenesis is crucial for improved patient care.
Abstract:
Three female patients with hypoplasia of the urinary bladder and associated congenital anomalies are described. All were first seen in early infancy with significant obstructive uropathy and were managed by early loop cutaneous ureterostomy. All have survived to adulthood and 2 patients have received a kidney transplant into an ileal conduit; 1 patient continues to do well with cutaneous ureterostomy only. Pathogenesis, management, and long-term outcome are discussed.