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Coffee and alcohol consumption as triggering factors for sudden cardiac death: case-crossover study
Jozica Selb Semerl1, Kristina Selb
1Institute of Public Health of the Republic Slovenia, Trubarjeva cesta 2, 1000 Ljubljana, Slovenia. Jozica.Selb@IVZ-RS.SI
Insights
Coffee and alcohol consumption can trigger sudden cardiac death, especially in individuals with existing heart disease risk factors. This study highlights the increased risk associated with these substances in vulnerable populations.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Sudden cardiac death (SCD) is a significant public health concern.
- Identifying triggers for SCD is crucial for prevention strategies.
- The role of common lifestyle factors like coffee and alcohol consumption in SCD requires further investigation.
Purpose of the Study:
- To estimate the relative risk of sudden cardiac death (SCD) following coffee or alcohol consumption.
- To investigate these risks in out-of-hospital SCD victims.
Main Methods:
- A case-crossover study design was employed.
- Data were collected via questionnaires from family members and physicians of SCD victims.
- Relative risk was calculated by comparing death occurrences within specific timeframes after consumption (1 hour for coffee, 2 hours for alcohol) versus non-consumption periods.
Main Results:
- The study included 309 out-of-hospital sudden cardiac death victims.
- Coffee consumption was associated with a relative risk of 1.73 (95% CI=1.13-2.65) for SCD within 1 hour.
- Alcohol consumption showed a higher relative risk of 3.00 (95% CI=1.61-5.68) for SCD within 2 hours.
Conclusions:
- Coffee and alcohol consumption are potential triggers for sudden cardiac death.
- The risk is particularly elevated in individuals with risk factors for ischemic heart disease.
- Lifestyle factors significantly modify the risk associated with coffee and alcohol intake in SCD events.
Aim:
To estimate the relative risk of triggering sudden cardiac death after coffee or alcohol consumption in out-of-hospital sudden cardiac death victims.
Methods:
A case-crossover design with usual frequency approach was used and the study population included persons who died out of hospital due to sudden cardiac death. By mailing 2 questionnaires, 1 to the family members of the deceased and the other to the attending physician, necessary data on the mode of cardiac death, life style, health, and several socio-demographic variables were obtained. Cases were those who died of sudden cardiac death within 1 hour after coffee consumption or within 2 hours after ingesting alcohol; but controls were those who died in the hours when they were not exposed to these stimulans. The relative risk of dying within exposed hours in comparison to non-exposed hours was parameter estimated for each risk factor.
Results:
Among 309 sudden cardiac death victims who died in the period from January 2000 to March 2001 in Slovenia, there were 253 men and 56 women with median age at death of 57.1 and 57.7, respectively. On average, each of them had 2.8 risk factors for ischemic heart disease, and the estimated relative risk of dying during 1 hour after coffee consumption was 1.73 (95% confidence interval [CI]=1.13-2.65), and within 2 hours after alcohol consumption 3.00 (95%CI=1.61-5.68). Within both coffee drinking and alcohol consuming groups, the relative risk was different among persons with different life style habits. It ranged from 1.50 for the coffee drinkers who had been receiving medication due to risk factors of heart diseases, to 2.63 for former alcohol drinkers. Among alcohol consumers it varied from 2.66 among those who were performing less than 104 hours of physical activity of six metabolic equivalents at least, to 52.15 among those of 90 heart beats or more per minute.
Conclusion:
Our research confirmed the hypothesis that coffee or alcohol consumption is a potential trigger for sudden cardiac death in persons with risk factors for ischemic heart disease.
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