Related Experiment Videos
Systolic hypertension in older persons
1University of Tennessee, School of Medicine, Memphis.
Advances in Internal Medicine
|January 1, 1992
Summary
Isolated systolic hypertension (ISH) is a major cardiovascular risk in older adults. Treating ISH effectively reduces cerebrovascular events, coronary heart disease, and overall cardiovascular mortality in this population.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Clinical Pharmacology
Background:
- Elevated systolic blood pressure (SBP) is the primary cardiovascular risk factor in individuals over 65.
- Isolated systolic hypertension (ISH) is prevalent in the elderly population.
Purpose of the Study:
- To evaluate the efficacy and safety of treating ISH in patients over 65.
- To determine the impact of ISH treatment on cardiovascular morbidity and mortality.
Main Methods:
- Analysis of clinical data from the SHEP main trial.
- Assessment of antihypertensive treatment efficacy and side effects in elderly patients.
Main Results:
- ISH can be treated effectively with minimal side effects in most elderly patients.
- Treatment of ISH significantly lowers cerebrovascular events, coronary heart disease, and total cardiovascular mortality.
Conclusions:
- Treating ISH is a proven strategy to reduce cardiovascular risk in older adults.
- Antihypertensive treatment recommendations for elderly patients with ISH are established.