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Updated: Aug 20, 2026

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
Immunotherapy for atherosclerosis: an emerging paradigm
Prediman K Shah1, Kuang-Yuh Chyu, Jan Nilsson
1Atherosclerosis Research Center, Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Abstract:
Experimental and clinical studies have implicated the immune system in atherogenesis and its complications. Recent studies have identified a complex dual role for the immune system: some aspects of the system play a proatherogenic role, whereas other aspects are atheroprotective. Suppression of proatherogenic immune responses and activation of antiatherogenic immune responses promise to emerge as novel strategies for the prevention and treatment of atherosclerotic vascular disease.
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