Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Barrett's esophagus].

W K H Kauer1, H J Stein, H J Dittler

  • 1Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München. wkauer@nt1.chir.med.tu-muenchen.de

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|December 8, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

Dorothea Liebermann-Meffert (*1930: †2020)-A Life Dedicated to Surgery.

World journal of surgery·2021
Same author

[High anastomotic leakage rate for robotic assisted esophagectomy-but not that high!]

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2019
Same author

[Leiomyoma of the esophagus : A further indication for robotic surgery?]

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2019
Same author

[Choice of procedure for achalasia treatment: a patient-oriented and results-based decision].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2017
Same author

[Laparoscopic Heller myotomy after failed POEM and multiple balloon dilatations : Better late than never].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2016
Same journal

[S3 Guideline "Adult soft tissue sarcomas"].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Synopsis-S3 guidelines pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Laparoscopic sentinel node navigation surgery in gastric cancer to reduce surgical radicality].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Future concepts for neoadjuvant and adjuvant treatment of (resectable) pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[ASCO guidelines for the treatment of stage III NSCLC part 4: indications for adjuvant therapy].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Surgical treatment of pancreatic cancer-What is new?]

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
See all related articles

The extent of intestinal metaplasia, a condition affecting the esophagus, correlates with the severity of gastroesophageal reflux disease (GERD). More severe GERD leads to greater intestinal metaplasia.

Area of Science:

  • Gastroenterology
  • Esophageal Diseases
  • Acid Reflux

Context:

  • Barrett's esophagus is linked to end-stage gastroesophageal reflux disease (GERD).
  • The relationship between GERD severity and the extent of intestinal metaplasia remains unclear.
  • Understanding this correlation is crucial for managing GERD and its complications.

Purpose:

  • To investigate the correlation between the severity of GERD and the extent of intestinal metaplasia in the esophagus.
  • To determine if increased exposure to gastric and duodenal contents relates to the degree of metaplasia.

Summary:

  • This study involved 142 patients with varying degrees of intestinal metaplasia and 20 healthy volunteers.
  • Participants underwent manometry and pH-bilirubin monitoring to assess esophageal function and reflux exposure.

Related Experiment Videos

  • Results showed that the extent of intestinal metaplasia correlated with increased exposure to gastric and duodenal juice and inversely with lower esophageal sphincter competence.

    • Impact:

    • The findings establish a direct relationship between the extent of intestinal metaplasia and the severity of GERD.
    • This research provides a clearer understanding of GERD's impact on esophageal tissue changes.
    • Highlights the importance of managing GERD severity to potentially mitigate the progression of intestinal metaplasia.