Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Solid pseudopapillary neoplasms. Enigmatic entity with female preponderance].

M Kosmahl1, K Peters, M Anlauf

  • 1Institut für Allgemeine Pathologie, Universitätsklinikum Schleswig-Holstein--Campus Kiel, Michaelisstrasse 11, 24105 Kiel, Germany. mkosmahl@path.uni-kiel.de

Der Pathologe
|December 8, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reproducibility and workflow efficiency of a novel software for quantitative coronary plaque characterization using photon-counting and energy-integrating detector computed tomography.

European journal of radiology·2026
Same author

Jupiter's X-Ray and UV Dark Polar Region.

Geophysical research letters·2022
Same author

Real-World Data for Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer (RELEVANT): A Retrospective Multicentric Analysis of Clinical Practice in Austria.

International journal of endocrinology·2020
Same author

Determination of deamidated isoforms of human insulin using capillary electrophoresis.

Journal of chromatography. A·2020
Same author

Failure of total hypophysectomy to remove intrasellar microadenoma in cushing's disease.

Endocrine pathology·2020
Same author

Prognostic relevance of topoisomerase II α and minichromosome maintenance protein 6 expression in colorectal cancer.

BMC cancer·2019

Solid pseudopapillary neoplasms (SPN) are rare pancreatic tumors predominantly affecting young women. While surgical removal offers a cure in most cases, SPN are considered low-grade malignant due to potential recurrence and metastasis.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Context:

  • Solid pseudopapilllary neoplasms (SPN) are a distinct group of pancreatic tumors.
  • These tumors predominantly affect young women and present as large, solitary masses.
  • Histological features include solid, pseudopapillary, and pseudocystic patterns.

Purpose:

  • To describe the key morphological and biological characteristics of pancreatic SPN.
  • To highlight the clinical behavior, including cure rates and malignant potential.
  • To emphasize the importance of differential diagnosis, particularly with neuroendocrine tumors.

Summary:

  • SPN are characterized by monomorphous tumor cells expressing vimentin, neuron-specific enolase, nuclear beta-catenin, and progesterone receptor.

Related Experiment Videos

  • Complete surgical resection achieves a cure in approximately 90% of patients.
  • Despite high cure rates, SPN are classified as low-grade malignant due to the possibility of recurrence and metastasis, with histological prediction of malignancy remaining challenging.

    • Impact:

    • Provides a concise overview of SPN for clinicians and researchers.
    • Underscores the need for accurate diagnosis and appropriate management strategies.
    • Contributes to understanding the biological behavior and classification of these rare pancreatic tumors.