Related Experiment Video
Updated: Aug 20, 2026

Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
Published on: January 6, 2012
Endometrial carcinoma in one horn of a bicornuate uterus
Julene R Moore1, Susan A Davidson, Meenakshi Singh
1Department of Pathology, University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA.
Background:
Tamoxifen therapy is related to endometrial adenocarcinoma. Bicornuate uteri are more common than assumed. There are a few reports of endometrioid carcinoma arising in a bicornuate uterus, but none of these discuss a serous papillary component or an association with tamoxifen therapy.
Case:
This is a case of a mixed endometrioid and serous papillary endometrial carcinoma arising in one horn of a bicornuate uterus. Multiple benign polyps were also present.
Conclusion:
Adequate tissue sampling of both horns is critical to arriving at a timely and accurate diagnosis of malignancy in patients with a bicornuate uterus.
Related Concept Videos
Ovarian Cycle
Histology of the Uterus
The endometrium is the...
Uterus and Cervix
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...
Ovaries
On the ovarian surface, a layer of cuboidal...

