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Baerveldt glaucoma implant in the management of refractory childhood glaucomas
Donald L Budenz1, Steven J Gedde, James D Brandt
1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Miami, Florida 33136, USA. dbudenz@med.miami.edu
Insights
The Baerveldt glaucoma drainage implant (GDI) effectively lowers intraocular pressure in children with refractory glaucomas. While generally safe, potential risks like retinal detachment warrant consideration in pediatric glaucoma management.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Glaucoma Management
Background:
- Pediatric glaucomas are complex conditions requiring effective long-term management.
- Glaucoma drainage implants (GDIs) are utilized when medical or other surgical treatments fail.
Purpose of the Study:
- To assess the efficacy and safety of the Baerveldt GDI in treating pediatric glaucomas.
- To compare outcomes between primary and secondary pediatric glaucoma cases.
Main Methods:
- Retrospective case series of 62 children (<18 years) who received Baerveldt GDI surgery.
- Evaluated intraocular pressure (IOP), complications, medication use, and visual acuity.
- Success defined by IOP control, absence of vision loss, and no further glaucoma surgery.
Main Results:
- Mean IOP decreased from 35.0 mmHg preoperatively to 17.6 mmHg postoperatively (P<0.001).
- Cumulative success rates were 85% at 6 months and 60% by 24 months.
- No significant differences in outcomes were observed between primary and secondary glaucoma groups.
Conclusions:
- Baerveldt GDI surgery demonstrates effectiveness for refractory glaucomas in children.
- Retinal detachment is a potential complication associated with the implant or other ocular factors.
Purpose:
To evaluate the effectiveness and safety of the Baerveldt glaucoma drainage implant (GDI) in the management of pediatric glaucomas.
Design:
Retrospective noncomparative case series.
Participants:
Sixty-two children younger than 18 years who underwent Baerveldt GDI surgery.
Main Outcome Measures:
Intraocular pressure (IOP), intraoperative and postoperative complications, number of glaucoma medications, and VA. Success was defined as IOP of <22 mmHg and > or =5 mmHg with or without medications, no loss of light perception, and no further surgical intervention for glaucoma. Outcomes were compared for patients with primary and secondary glaucomas.
Results:
Sixty-two eyes of 62 patients were identified. The mean patient age (+/- standard deviation) at time of Baerveldt glaucoma implant surgery was 6.5+/-5.6 years (range, 6 weeks-17 years). With an average follow-up of 23.4+/-21.7 months (range, 1-106), IOP was reduced from a mean of 35.0+/-8.7 mmHg (range, 17-54) preoperatively to 17.6+/-8.4 mmHg (range, 5-45) at last follow-up visit (P<0.001). Kaplan-Meier survival analysis showed a cumulative success of 85% at 6 months, 80% at 12 months, 67% at 24 months, and 60% in months 28 through 106. There was no difference between primary (N = 23) and secondary glaucoma (N = 39) patients in terms of length of follow-up, final IOP, number of medications, or cumulative success (P = 0.21).
Conclusion:
Baerveldt glaucoma implant surgery seems to be an effective treatment for primary and secondary refractory glaucomas in children. There is a risk of retinal detachment that may be related to the implant or other ocular conditions.
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