Related Experiment Video
Updated: Aug 20, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Lens-sparing vitrectomy for stage 4 retinopathy of prematurity
G Baker Hubbard1, D Hunter Cherwick, Gabriela Burian
1The Emory Eye Center, Emory University School of Medicine, Atlanta, Georgia 30322, USA. baker_hubbard@emoryhealthcare.org
Purpose:
To investigate the anatomic results of lens-sparing vitrectomy for tractional stage 4 retinopathy of prematurity (ROP).
Design:
Retrospective, noncomparative consecutive case series.
Participants:
Thirty-seven eyes (24 patients) with tractional stage 4 ROP.
Intervention:
Lens-sparing vitrectomy.
Main Outcome Measure:
Anatomic status of the retina.
Results:
Twenty-five eyes had stage 4A ROP, and 12 eyes had stage 4B ROP. With a median follow-up of 13 months (range, 6-27), 32 of 37 eyes (86%) had complete reattachment of the retina. Among eyes with 4A ROP, 21 of 25 eyes (84%) had complete retinal reattachment. Among eyes with 4B ROP, 11 of 12 eyes (92%) had complete retinal reattachment. At last follow-up, 29 of 37 eyes (78%) were able to fix and follow.
Conclusions:
These results indicate that lens-sparing vitrectomy is effective for achieving retinal reattachment in tractional stage 4 ROP. This article contains additional online-only material available at .

