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[Breastfeeding and maternal medications]
Roberto G Chaves1, Joel A Lamounier
1Faculdade de Fisioterapia, Universidade de Itaúna, MG.
Jornal De Pediatria
|December 8, 2004
Summary
Most drugs are safe for breastfeeding mothers and infants. However, certain medications like antineoplastics and drugs of abuse should be avoided, while others require careful consideration due to potential risks.
Area of Science:
- Pharmacology
- Pediatrics
- Obstetrics
Background:
- Informed drug administration during breastfeeding is crucial for maternal and infant health.
- Limited data exists on the safety of many medications for breastfeeding infants.
Purpose of the Study:
- To provide information on the safe and adequate administration of drugs during breastfeeding.
- To review the compatibility of various medications with lactation.
Main Methods:
- A review of MEDLINE and Lilacs databases (1993-2004) using keywords: breastfeeding, lactation, drugs, medicines.
- Inclusion of additional updated references from articles and books.
Main Results:
- The majority of drugs are compatible with breastfeeding.
- Antineoplastic drugs, radiopharmaceuticals, and drugs of abuse are generally contraindicated.
- Some drugs necessitate caution due to potential adverse effects or impact on milk supply.
Conclusions:
- The risk-benefit principle guides drug prescription for lactating mothers.
- Prioritize well-studied drugs with low milk transfer and minimal infant risk.
- Avoid medications that reduce milk production; use galactagogues sparingly.