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Updated: Aug 14, 2026

The Intra-Aortic Balloon Pump
Published on: February 5, 2021
Complications of major aortic and lower extremity vascular surgery
J Nana Ghansah1, J Thomas Murphy
1Department of Anesthesiology, University of Kentucky, College of Medicine, H A Chandler Medical Center, Lexington, KY 40536-0293, USA.
Insights
This review covers complications of open aortic repair and endovascular aortic repair (EVAR). EVAR shows promise for fewer complications, but carries unique risks like endoleaks and requires ongoing surveillance.
Area of Science:
- Vascular Surgery
- Interventional Radiology
Background:
- Atheromatous disease of the aortoiliac and distal arteries necessitates invasive interventions.
- Patient risk factor management has improved outcomes, but complications remain significant across organ systems.
- Cardiovascular complications, infection (aortoenteric fistula), paraplegia, and multiorgan failure are serious risks of open repair.
Purpose of the Study:
- To review perioperative and postoperative complications associated with open aortic repair and lower-extremity revascularization.
- To examine endovascular aortic repair (EVAR), its unique complications, and compare it to open repair.
- To discuss anesthesia considerations for major vascular surgery and EVAR, including acute abdominal aortic aneurysm management.
Main Methods:
- Review of perioperative and postoperative complications of open aortic repair and lower-extremity revascularization.
- Review of endovascular aortic repair (EVAR) technology, its development, and associated complications.
- Discussion of anesthesia-related concerns for both open and endovascular procedures.
Main Results:
- Open repair and vascular surgery for infrainguinal disease carry significant risks, including cardiovascular events and organ damage.
- EVAR, a hybrid surgical and radiological intervention, presents similar complications to open repair but potentially less frequently.
- Unique EVAR complications include endoleaks, endoprosthesis migration, and need for surgical conversion; potential benefits include reduced blood loss and hospitalization.
Conclusions:
- EVAR offers potential advantages over open repair, but risks such as aneurysm recurrence and the need for prolonged surveillance and secondary procedures exist.
- Understanding and managing complications, including anesthesia-related issues, is crucial for both open and endovascular aortic interventions.
- EVAR represents an evolving technology with specific challenges and benefits that require careful consideration in patient management.
Abstract:
Atheromatous disease and invasive intervention of the aortoiliac and distal arteries are common. Morbidity and mortality have been reduced through understanding and management of patient risk factors. Complications of this form of treatment affect all organ systems; mortality is most frequently caused by a cardiovascular complication (eg, myocardial infarction). Infection, leading to aortoenteric fistula is a dreaded complication, and paraplegia, though rare, is a devastating outcome. Multiorgan failure and death may result from a systemic inflammatory response syndrome. Vascular surgery for infrainguinal disease also has a significant cardiovascular complication rate. Resulting complications may affect all organs; loss of an extremity may occur. The first part of this article reviews perioperative and postoperative complications of open aortic repair and lower-extremity revascularization and addresses the issue of regional anesthesia for major vascular surgery. The second part reviews endovascular aortic repair (EVAR). EVAR is a new intervention that combines surgery and radiology. Complications of EVAR are similar to open repair, but early results suggest they may be less frequent. New technology leads to new complications; endoleaks, migration of the endoprosthesis, and surgical conversion are unique to EVAR. The benefits of EVAR may be less blood loss, shorter hospitalization, and less cardiovascular stress; the risks may be aneurysm recurrence, prolonged surveillance and repeated secondary procedures. The development of EVAR, the complications, and the anesthesia-related concerns of EVAR, including its use in management of acute abdominal aortic aneurysm are reviewed.
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