Related Experiment Video
Updated: Aug 11, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Economics of antibiotic use policies
1State University of New York at Buffalo, and Clinical Outcomes and Pharmacoeconomics, CPL Associates LLC, Buffalo, New York 14226-1727, USA. paladino@cplassociates.com
Abstract:
Today more than ever, hospitals must effectively manage the use of antibiotics to control costs and preserve their usefulness. To achieve this goal, antibiotic management must evolve from overly simplistic antibiotic cost containment to more complex, multidisciplinary, appropriate use programs that are founded on clinical outcomes-based pharmacoeconomic analyses. This article addresses common cost-containment activities as they relate to antibiotics and examines their consequences. Examples of successful antimicrobial stewardship and the role of pharmacoeconomic analyses also are provided. Cost-effectiveness studies of cefepime are presented to illustrate the utility of these analyses and provide information that can form the basis for decisions regarding placement of cefepime on hospital formularies.
Related Concept Videos
Antibiotic Selection
Production of Antibiotics
Microbiota Modulation by Antibiotics
Mechanism of Antibiotic Resistance in MRSA
Inhibitors of Bacterial Protein Synthesis
Clinical Significance of Antibiotic Resistance

