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Updated: Aug 20, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
Published on: August 1, 2013
Exploiting dendritic cells for active immunotherapy of cancer and chronic infection
1Tumor Vaccine Center, NYU Cancer Institute, New York University School of Medicine, New York, NY, USA.
Abstract:
Dendritic cells (DC) are important antigen-presenting cells (APC) that can prime naive T-cells and control lymphocyte-mediated adaptive immune responses with respect to magnitude, memory, and self-tolerance. Understanding the biology of these cells is central to the development of new generation immunotherapies for cancer and chronic infection. This chapter presents a brief overview of DC biology and the preparation and use of DC-based vaccines.
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