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[Partial androgen deficiency in the aging male]
Virya Castro-Acuña1, Lizbet Martínez-Martínez, Fernando Larrea
1Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, DF.
Abstract:
The presence of clinical manifestations of androgen deficiency is a frequent condition in men older than 50 years. Recently, there has been a growing interest to study whether the clinical, endocrine, physical and psychological manifestations in the elderly men are associated to androgen deficiency, as well as if hormonal replacement, in these individuals, contributes to improve the quality of life through its effects upon the mass and muscular strength, bone fractures prevention and on the maintenance of sexual drive. In the present review article it is established that partial androgen deficiency in the aging male represents a controversial clinical condition of multifactorial origin, which is accompanied of several alterations on various endocrine systems. An analysis of its long-term consequences and therapeutical approach are also reviewed.
Insights
Partial androgen deficiency is common in men over 50. This review explores its links to various symptoms and the benefits of hormone replacement therapy for aging men.
Area of Science:
- Endocrinology
- Geriatrics
- Men's Health
Context:
- Androgen deficiency is prevalent in aging males, impacting clinical, endocrine, physical, and psychological health.
- Growing interest in understanding the multifactorial origins and consequences of this condition.
Purpose:
- To review the association between clinical manifestations and androgen deficiency in elderly men.
- To evaluate the efficacy of hormonal replacement therapy in improving quality of life.
Summary:
- Partial androgen deficiency in aging males is a complex condition with multifactorial origins.
- It is associated with various endocrine system alterations and diverse clinical symptoms.
- Hormonal replacement therapy is explored for its potential benefits.
Impact:
- Provides insights into the management of androgen deficiency in aging men.
- Highlights the role of hormone replacement therapy in improving health outcomes.
- Contributes to the understanding of age-related endocrine changes.
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