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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Pentacyclic triterpenoids from Aster ageratoides var. pilosus
Fu-Lin Yan1, Ai-Xia Wang, Zhong-Jian Jia
1College of Chemistry and Chemical Engineering, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
Abstract:
Two new pentacyclic triterpenoids, 2beta,3beta,16alpha-trihydroxyl-24alpha-al-olean-12-en-28-oic acid (1), 2beta,3beta-dihydroxyl-16-O-beta-D-glucopyranose-24alpha-al-olean-12-en-28-oic acid (2) and two known pentacyclic triterpenoids were isolated from the roots of Aster ageratoides var. pilosus. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2D NMR). In addition, the anti-bacterial activity and anti-tumor activity of compound 2 were tested.
